According to AABB standards, Fresh Frozen Plasma must be infused within what time frame following thawing?

Fresh Frozen Plasma (FFP) must be infused within 24 hours following thawing according to AABB standards. This time frame is critical because once FFP has been thawed, it begins to lose its clotting factors and other important components that are crucial for its therapeutic efficacy. Specifically, factors V and VIII are of particular concern, as their activity diminishes over time after thawing. Therefore, to ensure that the patient receives the maximum benefit from the infusion and to optimize the hemostatic properties of the plasma, it is essential that it is administered within the 24-hour window. Adhering to this guideline helps in maintaining the safety and effectiveness of blood component transfusions.