Given Rh antisera reactions showing 4+ for anti-D and 3+ for anti-C, what is the individual's most probable genotype?

Prepare for the Technologist in Blood Banking (BB (ASCP)) Test with flashcards and multiple choice questions, each question has tips and explanations. Get thoroughly ready for your exam!

The individual exhibiting a 4+ reaction for anti-D indicates a strong expression of the D antigen, suggesting the presence of at least one D allele in their genotype. The reaction of 3+ for anti-C indicates that the individual has some level of expression of the C antigen, which suggests at least one C allele is present.

When considering the genotype options, a phenotype that displays strong D (indicated by the 4+ reaction for anti-D) and moderately strong C (indicated by the 3+ reaction for anti-C) aligns with the D and C alleles present in option D, DCe/dce. This genotype contains one allele that expresses the strong D antigen as well as one C antigen, while also having a d allele which does not express D or C.

The other options do not accurately represent the 4+ reaction for anti-D and 3+ reaction for anti-C in the same manner. The configuration DCe/dce maintains the required strong expression of D and a lower expression of C that corresponds to the serological reactions observed, making it the most probable genotype for this scenario.

Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy