If a patient's red cells react as anti-D 4+, anti-C 0, and anti-E 0, which genotype is consistent with these results?

The correct answer reflects the genotype that aligns with the observed serological results of the patient's red cells. In this case, the patient shows a strong positive reaction with anti-D (4+) and no reaction with anti-C or anti-E.

A strong anti-D reaction indicates the presence of the D antigen on the red blood cells, which is consistently seen in genotypes that have at least one D allele. In the scenario given, the specific genotype R0R0 indicates that the individual is homozygous for the R0 allele, which is associated with the D antigen and does not possess the C or E antigens.

The absence of reactivity with anti-C and anti-E, specifically indicated by the results showing "0" reactions for both, supports the R0R0 genotype, as this genotype does not express the C or E antigens.

In summary, the interpretation of the serological results aligns perfectly with the R0R0 genotype, making it the most appropriate choice for this question.