If the seal is entered on a unit of Red Blood Cells stored at 1 ˚C to 6 ˚C, what is the maximum allowable storage period, in hours?

The maximum allowable storage period for a unit of Red Blood Cells (RBCs) after the seal has been broken is crucial for maintaining the blood product's integrity and ensuring patient safety. Once the seal is entered, the storage time is limited due to the risk of bacterial contamination and the potential deterioration of the blood components.

For RBCs that are stored at the temperature range of 1 ˚C to 6 ˚C, the established guideline is that they can be stored for a maximum of 24 hours after entry of the seal. This allows for a safe time for transfusion while minimizing the risk of adverse events related to bacterial growth.

This regulation is in place because, after the seal is broken, the RBCs are exposed to the environment, which can introduce pathogens and compromise the viability of the blood unit. Therefore, adhering to the 24-hour limit ensures that transfusions are conducted safely, utilizing fresh components that are less likely to cause complications for the patient.

In summary, 24 hours is the maximum allowable storage period for Red Blood Cells after the seal is entered while stored at 1 ˚C to 6 ˚C, prioritizing safety and efficacy in blood transfusion practices.