What is the most probable genotype of a patient who shows positive reactions with anti-D, anti-C, anti-E, anti-c, anti-e, and negative with anti-f?

To determine the most probable genotype based on the given serological reactions, it’s important to analyze the presence or absence of specific antigens related to the Rh blood group system.

The positive reactions with anti-D, anti-C, anti-E, anti-c, and anti-e indicate that the patient expresses the D antigen, as well as the C, E, c, and e antigens on their red blood cells. The fact that anti-f is negative suggests that the patient does not possess the f antigen, which is formed by the presence of both C and E antigens.

The genotype that best matches this pattern is R1R2. This genotype includes the D antigen (R1), C antigen (R1), and E antigen (R2), which aligns with the positive reactions observed. The heterozygous state of R1R2 suggests the presence of both C and c, as well as E and e, indicating that the patient will react to anti-C and anti-E while still lacking a specific combination that leads to the formation of the f antigen.

In contrast, the other genotypes (R2r'', R2r, and RzRz) do not fully align with the observed pattern of reactivity. For instance