What is the shelf life of Cryoprecipitated AHF if maintained in the frozen state at -18 ˚C or below?

Cryoprecipitated AHF (antihemophilic factor), when stored in the frozen state at -18 °C or lower, has a shelf life of 12 months. This specific duration is established based on regulatory guidelines that dictate how long such products retain their effectiveness and safety when properly frozen.

During this time, the clotting factors, particularly factor VIII and fibrinogen, remain stable, allowing for effective treatment when thawed for patient use. It is crucial for healthcare providers to adhere to these storage recommendations to ensure optimal clinical outcomes for patients requiring this treatment. Understanding the shelf life is fundamental in blood banking, as it helps in managing inventory, ensuring safety, and maximizing the utility of blood products.