What phenotype would most likely describe the red cells of a nonsecretor (se/se)?

The correct choice, Le (a+b-), accurately reflects the phenotype of red cells from a nonsecretor (se/se) individual. In blood group genetics, the Lewis blood group system is influenced by the presence of the secretor gene (Se). Individuals who are secretors (Se/Se or Se/se) express Lewis antigens on their red blood cells, as well as in their secretions. Conversely, nonsecretors (se/se) do not produce the enzyme required to convert the precursor substance into the Lewis antigens in body fluids.

In the case of a nonsecretor, the typical Lewis phenotype would be characterized by the absence of the Le(a) antigen and the presence of the Le(b) antigen. A nonsecretor will have Le(a-b-) phenotypically when they lack both Lewis A and Lewis B antigens on their red cells. However, it is also important to consider the expression of Lewis antigens, which can be influenced by the individual's secretor status, leading to the presence or absence of specific antigens depending on their genetic background.

Given that nonsecretors do not generate Lewis A antigen, but may express Lewis B, the nonsecretor phenotype usually results in Le(a+b-) or Le