Which factor constitutes permanent rejection status for a blood donor?

A confirmed positive test for HBsAg indicates that an individual is infected with hepatitis B virus and is therefore at risk for transmitting the virus to recipients of blood products. This status leads to a permanent deferral from donating blood, as it is crucial to ensure the safety of the blood supply.

Individuals who test positive for HBsAg must be permanently excluded from donation because they can carry the virus even if they do not exhibit any symptoms. The criteria for permanent deferral are stringent, particularly in cases of infectious diseases that pose significant health risks to patients receiving blood. Thus, a previous confirmation of hepatitis B infection categorically leads to a permanent rejection status for blood donors to protect patients from potential viral transmission.