Which red cell typing is most commonly found in the African American donor population?

The most commonly found red cell typing in the African American donor population is Fy(a-b-). This phenotype is characterized by the absence of both the Fya and Fyb antigens, which are part of the Duffy blood group system. Approximately 68% of African Americans are known to express this phenotype, making it significantly more prevalent in this population compared to Caucasians, where the frequency is much lower.

The Duffy antigens are particularly relevant when considering blood transfusions and organ transplants, as individuals with the Fy(a-b-) phenotype can produce antibodies against Fya and Fyb antigens. This can lead to complications if they receive blood from donors who express these antigens. Understanding the prevalence of the Fy(a-b-) phenotype in African Americans is crucial for blood banks in order to match donors and recipients accurately and minimize transfusion reactions.

The other options represent less frequent phenotypes in this population, which helps to emphasize the distinct genetic and epidemiological factors influencing blood group distribution among different ethnic groups.